There are many reasons for this to happen, check the following in sequence:

1. Open IIS Manager
   
   For IIS 6 do the following:
   A) Click on Web Service Extensions from the left window.
   B) On the right window make sure that ASP.NET v2.0.50727 is in Allowed status.
   
   For IIS7 do the following:
   A) Select ISAPI and CGI Restrictions,
   B) Make sure ASP.NET v2.0.50727 is Allowed
   
   Now try to run OfficeClip Systemtest (https://your-machine-name/officeclip/systemtest.aspx) and see if it works.
   
   
2. Open the following file on your notepad: %windir%\drivers\etc\Hosts. Comment any line (with a # sign on the first line) that looks like ::1 localhost
   
   Try to run OfficeClip Systemtest (https://your-machine-name/officeclip/systemtest.aspx)
   
   
3. If nothing works, reinstall the IIS and then re-register the ASP.Net by doing the following:
   
   A) Go to Control Panel > Add or Remove Programs > Add/Remove Windows Component
   B) Uncheck the Internet Information Services (and ASP.Net if present) and then Click Ok and then Next.
   C) After it uninstalls, repeat Step A and again check mark the Internet Information Services (and ASP.Net if present) and then Click Ok and then Next.
   ** Note ** At this point it may ask for the Windows CD so make sure you have it handy.
   D) Now bring up a DOS command prompt and then run these commands:
   %windir%\microsoft.net\framework\v2.0.50727\aspnet_regiis.exe -u
   %windir%\microsoft.net\framework\v2.0.50727\aspnet_regiis.exe -i -enable
   E) Finally from the Control panel uninstall OfficeClip and then reinstall it
   **Note ** The above steps are different for Vista and IIS 7, Usually this step is not required in IIS7 machines. But if you have to do it, please consult IIS 7/ Vista documentation.
   
   
4. If it still does not work, fire an email to OfficeClip Support (ocsupport at officeclip dot com)

Edited by user Wednesday, January 20, 2010 6:55:53 AM(UTC)  | Reason: Not specified